TY - GEN AU - Holmes,Ian P AU - Gaines,Simon AU - Watson,Steve P AU - Lorthioir,Olivier AU - Walker,Adam AU - Baddeley,Suzanne J AU - Herbert,Shane AU - Egan,Danielle AU - Convery,Máire A AU - Singh,Onkar M P AU - Gross,Jeffrey W AU - Strelow,John M AU - Smith,Robert H AU - Amour,Augustin J AU - Brown,David AU - Martin,Stephen L TI - The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors SN - 1464-3405 PY - 2009///1130 KW - Animals KW - Binding Sites KW - Carboxylic Acids KW - chemical synthesis KW - Crystallography, X-Ray KW - Drug Design KW - Guinea Pigs KW - Humans KW - Matrix Metalloproteinase 12 KW - metabolism KW - Matrix Metalloproteinase Inhibitors KW - Protease Inhibitors KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2009.07.155 ER -