TY - GEN AU - Sidique,Shyama AU - Shiryaev,Sergey A AU - Ratnikov,Boris I AU - Herath,Ananda AU - Su,Ying AU - Strongin,Alex Y AU - Cosford,Nicholas D P TI - Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase SN - 1464-3405 PY - 2009///1130 KW - Allosteric Regulation KW - Antiviral Agents KW - chemical synthesis KW - Drug Design KW - Half-Life KW - Hydrogen-Ion Concentration KW - Hydrolysis KW - Pyrazoles KW - RNA Helicases KW - antagonists & inhibitors KW - Serine Endopeptidases KW - metabolism KW - Serine Proteinase Inhibitors KW - Structure-Activity Relationship KW - Viral Nonstructural Proteins KW - West Nile Fever KW - drug therapy KW - West Nile virus KW - drug effects N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.bmcl.2009.07.150 ER -