TY  - GEN
AU  - Kumar,Manoj
AU  - Vijayakrishnan,Rajakrishnan
AU  - Subba Rao,Gita
TI  - In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery
SN  - 1573-501X
PY  - 2011///0228
KW  - Amino Acid Sequence
KW  - Antitubercular Agents
KW  - chemistry
KW  - Binding Sites
KW  - Computational Biology
KW  - methods
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Folic Acid Antagonists
KW  - Humans
KW  - Hydrogen Bonding
KW  - drug effects
KW  - Ligands
KW  - Methotrexate
KW  - Microbial Sensitivity Tests
KW  - Molecular Dynamics Simulation
KW  - Molecular Sequence Data
KW  - Mycobacterium tuberculosis
KW  - Ornithine
KW  - analogs & derivatives
KW  - Peptides
KW  - Pterins
KW  - Reproducibility of Results
KW  - Substrate Specificity
KW  - Tetrahydrofolate Dehydrogenase
KW  - metabolism
KW  - Triazines
KW  - Tuberculosis
KW  - drug therapy
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s11030-009-9172-6
ER  -