TY - GEN AU - Calvo,Fernando AU - Crespo,Piero TI - Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors SN - 1939-4586 PY - 2010///0330 KW - Animals KW - COS Cells KW - metabolism KW - Chlorocebus aethiops KW - Enzyme Activation KW - drug effects KW - Guanosine Diphosphate KW - HeLa Cells KW - Humans KW - Ionomycin KW - pharmacology KW - Lysophospholipids KW - Membrane Proteins KW - chemistry KW - Monomeric GTP-Binding Proteins KW - Organelles KW - Prenylation KW - Protein Interaction Mapping KW - Protein Processing, Post-Translational KW - Protein Structure, Tertiary KW - RNA, Small Interfering KW - Recombinant Fusion Proteins KW - physiology KW - Structure-Activity Relationship KW - Subcellular Fractions KW - Substrate Specificity KW - cdc42 GTP-Binding Protein KW - ras Guanine Nucleotide Exchange Factors KW - antagonists & inhibitors KW - ras-GRF1 KW - genetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1091/mbc.e09-03-0212 ER -