Watson, Jane L <br/><br/>
Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.  [electronic resource] 

 -  Molecular carcinogenesis  Jan 2010 
 - 13-24 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1098-2744 
<br/><br/><label>Standard No.: </label>10.1002/mc.20571  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Curcumin--pharmacology<br/>Dose-Response Relationship, Drug<br/>Down-Regulation--drug effects<br/>Enzyme Activation--drug effects<br/>Female<br/>Humans<br/>Inhibitor of Apoptosis Proteins<br/>Microtubule-Associated Proteins--metabolism<br/>Oncogene Protein v-akt--metabolism<br/>Ovarian Neoplasms--genetics<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>RNA Interference<br/>Signal Transduction--drug effects<br/>Spheroids, Cellular--drug effects<br/>Survivin<br/>Time Factors<br/>Tumor Suppressor Protein p53--genetics<br/>p38 Mitogen-Activated Protein Kinases--metabolism