TY  - GEN
AU  - Hanessian,Stephen
AU  - Therrien,Eric
AU  - Zhang,Jianbin
AU  - Otterlo,Willem van
AU  - Xue,Yafeng
AU  - Gustafsson,David
AU  - Nilsson,Ingemar
AU  - Fjellström,Ola
TI  - From natural products to achiral drug prototypes: potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs
SN  - 1464-3405
PY  - 2009///1123
KW  - Animals
KW  - Cattle
KW  - Crystallography, X-Ray
KW  - Humans
KW  - Models, Molecular
KW  - Protein Binding
KW  - Pyridones
KW  - chemical synthesis
KW  - Serine Proteinase Inhibitors
KW  - Thrombin
KW  - antagonists & inhibitors
KW  - Trypsin
KW  - metabolism
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2009.07.107
ER  -