Hanessian, Stephen <br/><br/>
From natural products to achiral drug prototypes: potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Sep 2009 
 - 5429-32 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2009.07.107  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cattle<br/>Crystallography, X-Ray<br/>Humans<br/>Models, Molecular<br/>Protein Binding<br/>Pyridones--chemical synthesis<br/>Serine Proteinase Inhibitors--chemical synthesis<br/>Thrombin--antagonists & inhibitors<br/>Trypsin--metabolism