TY - GEN AU - Pajic,Marina AU - Iyer,Jayasree K AU - Kersbergen,Ariena AU - van der Burg,Eline AU - Nygren,Anders O H AU - Jonkers,Jos AU - Borst,Piet AU - Rottenberg,Sven TI - Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer SN - 1538-7445 PY - 2009///0915 KW - ATP Binding Cassette Transporter, Subfamily B KW - antagonists & inhibitors KW - Animals KW - Antibiotics, Antineoplastic KW - pharmacology KW - Breast Neoplasms KW - drug therapy KW - Disease Models, Animal KW - Doxorubicin KW - Drug Resistance, Neoplasm KW - genetics KW - Female KW - Gene Expression Regulation, Neoplastic KW - physiology KW - Genes, BRCA1 KW - Genes, p53 KW - Humans KW - Mice KW - Mice, Knockout KW - Quinolines KW - Tumor Burden KW - Up-Regulation KW - ATP-Binding Cassette Sub-Family B Member 4 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-09-0041 ER -