Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Nov 2009
- 555-62 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1521-0103
10.1124/jpet.109.155770 doi
3,4-Dihydroxyphenylacetic Acid--metabolism Amphetamine-Related Disorders--metabolism Animals Biogenic Monoamines--metabolism Brain Chemistry--drug effects Central Nervous System Stimulants--administration & dosage Chromatography, High Pressure Liquid Cues Dopamine--metabolism Dopamine Plasma Membrane Transport Proteins--metabolism Extinction, Psychological Male Methamphetamine--administration & dosage Neostriatum--drug effects Prefrontal Cortex--drug effects Rats Rats, Long-Evans Recurrence Self Administration Serotonin Plasma Membrane Transport Proteins--metabolism