Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death. [electronic resource]
- Molecular cancer therapeutics Aug 2009
- 2211-20 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1538-8514
10.1158/1535-7163.MCT-09-0327 doi
Apoptosis Boronic Acids--pharmacology Bortezomib Carcinoma, Squamous Cell--drug therapy Cell Line, Tumor Enzyme Inhibitors--pharmacology Head and Neck Neoplasms--drug therapy Humans Pyrazines--pharmacology STAT3 Transcription Factor--antagonists & inhibitors Signal Transduction--drug effects Up-Regulation