An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. [electronic resource]
- Science (New York, N.Y.) Aug 2009
- 995-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1095-9203
10.1126/science.1173275 doi
Animals Breeding Chondrocytes--metabolism Dogs--anatomy & histology Evolution, Molecular Extremities--anatomy & histology Fibroblast Growth Factor 4--genetics Gene Duplication Gene Expression Regulation Gene Frequency Genes, Duplicate Genome-Wide Association Study Haplotypes Humerus--metabolism Long Interspersed Nucleotide Elements Oligonucleotide Array Sequence Analysis Pedigree Phenotype Polymorphism, Single Nucleotide Regulatory Sequences, Nucleic Acid Retroelements--genetics Selection, Genetic