TY - GEN AU - Doucet,Nicolas AU - Watt,Eric D AU - Loria,J Patrick TI - The flexibility of a distant loop modulates active site motion and product release in ribonuclease A SN - 1520-4995 PY - 2009///1102 KW - Amino Acid Sequence KW - Animals KW - Catalytic Domain KW - Cattle KW - Cytidine Monophosphate KW - metabolism KW - Eosinophil Cationic Protein KW - chemistry KW - Humans KW - Models, Molecular KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Nuclear Magnetic Resonance, Biomolecular KW - Pliability KW - Protein Folding KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Recombinant Fusion Proteins KW - Ribonuclease, Pancreatic KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1021/bi900830g ER -