Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. [electronic resource]
- Blood Sep 2009
- 2837-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2009-01-197640 doi
Adolescent Adult Aged Aged, 80 and over Cells, Cultured Child Child, Preschool Cohort Studies Complement Activation--genetics Complement C3-C5 Convertases--genetics Complement System Proteins--genetics Endothelial Cells--metabolism Family Female Hemolytic-Uremic Syndrome--genetics Humans Infant Infant, Newborn Male Middle Aged Models, Molecular Mutant Proteins--physiology Pedigree Young Adult