TY - GEN AU - Baragi,Vijaykumar M AU - Becher,Gabriel AU - Bendele,Alison M AU - Biesinger,Ralf AU - Bluhm,Harald AU - Boer,Jürgen AU - Deng,Hongbo AU - Dodd,Rory AU - Essers,Michael AU - Feuerstein,Tim AU - Gallagher,Brian M AU - Gege,Christian AU - Hochgürtel,Matthias AU - Hofmann,Michael AU - Jaworski,Andreas AU - Jin,Lixia AU - Kiely,Andrew AU - Korniski,Brian AU - Kroth,Heiko AU - Nix,Darrell AU - Nolte,Bert AU - Piecha,Dorothea AU - Powers,Timothy S AU - Richter,Frank AU - Schneider,Matthias AU - Steeneck,Christoph AU - Sucholeiki,Irving AU - Taveras,Arthur AU - Timmermann,Andreas AU - Van Veldhuizen,Joshua AU - Weik,Juergen AU - Wu,Xinyuan AU - Xia,Bing TI - A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models SN - 0004-3591 PY - 2009///0914 KW - Animals KW - Cartilage, Articular KW - drug effects KW - Cattle KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - pharmacology KW - Humans KW - Interleukin-1alpha KW - Iodoacetates KW - Iodoacetic Acid KW - adverse effects KW - Male KW - Matrix Metalloproteinase Inhibitors KW - Musculoskeletal System KW - Oncostatin M KW - Osteoarthritis KW - chemically induced KW - Rats KW - Rats, Sprague-Dawley KW - Treatment Outcome N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/art.24629 ER -