Baragi, Vijaykumar M

A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. [electronic resource] - Arthritis and rheumatism Jul 2009 - 2008-18 p. digital

Publication Type: Journal Article

0004-3591

10.1002/art.24629 doi


Animals
Cartilage, Articular--drug effects
Cattle
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Humans
Interleukin-1alpha--pharmacology
Iodoacetates--pharmacology
Iodoacetic Acid--adverse effects
Male
Matrix Metalloproteinase Inhibitors
Musculoskeletal System--drug effects
Oncostatin M--pharmacology
Osteoarthritis--chemically induced
Rats
Rats, Sprague-Dawley
Treatment Outcome