Lu, Jie

Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 2009 - 11697-702 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.0905930106 doi


Animals
Antineoplastic Agents, Alkylating--therapeutic use
Blotting, Western
Cell Cycle Proteins--metabolism
DNA Damage
Dacarbazine--analogs & derivatives
Enzyme Inhibitors--pharmacology
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Regulation, Enzymologic--drug effects
Glioblastoma--drug therapy
Mice
Mice, SCID
Neuroblastoma--drug therapy
Protein Phosphatase 2--antagonists & inhibitors
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Temozolomide
Polo-Like Kinase 1