TY  - GEN
AU  - Bunnelle,William H
AU  - Tietje,Karin R
AU  - Frost,Jennifer M
AU  - Peters,Dan
AU  - Ji,Jianguo
AU  - Li,Tao
AU  - Scanio,Marc J C
AU  - Shi,Lei
AU  - Anderson,David J
AU  - Dyhring,Tino
AU  - Grønlien,Jens H
AU  - Ween,Hilde
AU  - Thorin-Hagene,Kirsten
AU  - Meyer,Michael D
TI  - Octahydropyrrolo[3,4-c]pyrrole: a diamine scaffold for construction of either alpha4beta2 or alpha7-selective nicotinic acetylcholine receptor (nAChR) ligands. Substitutions that switch subtype selectivity
SN  - 1520-4804
PY  - 2009///0825
KW  - Animals
KW  - Binding Sites
KW  - Cell Line
KW  - Diamines
KW  - chemistry
KW  - Humans
KW  - Ligands
KW  - Nicotinic Agonists
KW  - Pyrroles
KW  - Rats
KW  - Receptors, Nicotinic
KW  - metabolism
KW  - Structure-Activity Relationship
KW  - Substrate Specificity
KW  - alpha7 Nicotinic Acetylcholine Receptor
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm900249k
ER  -