TY - GEN AU - Gruber,Thomas AU - Hermann-Kleiter,Natascha AU - Hinterleitner,Reinhard AU - Fresser,Friedrich AU - Schneider,Rainer AU - Gastl,Günther AU - Penninger,Josef M AU - Baier,Gottfried TI - PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation SN - 1937-9145 PY - 2009///0928 KW - Adaptor Proteins, Signal Transducing KW - genetics KW - Animals KW - CD28 Antigens KW - Isoenzymes KW - Lymphocyte Activation KW - Mice KW - Mice, Knockout KW - Protein Kinase C KW - Protein Kinase C-theta KW - Proto-Oncogene Proteins c-cbl KW - Receptors, Antigen, T-Cell KW - T-Lymphocytes KW - enzymology KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scisignal.2000046 ER -