TY - GEN AU - LaMontagne,Kenneth R AU - Butler,Jeannene AU - Borowski,Virna B AU - Fuentes-Pesquera,Angel R AU - Blevitt,Jonathan M AU - Huang,Shenlin AU - Li,Ronghua AU - Connolly,Peter J AU - Greenberger,Lee M TI - A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo SN - 1573-7209 PY - 2010///0111 KW - Administration, Oral KW - Angiogenesis Inhibitors KW - administration & dosage KW - Animals KW - Cell Movement KW - drug effects KW - Cells, Cultured KW - Endothelial Cells KW - Female KW - HCT116 Cells KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Nude KW - Mice, Transgenic KW - Models, Biological KW - Neoplasms KW - drug therapy KW - Oximes KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Substrate Specificity KW - Vascular Endothelial Growth Factor A KW - pharmacology KW - Vascular Endothelial Growth Factor Receptor-2 KW - antagonists & inhibitors KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s10456-009-9151-7 ER -