LaMontagne, Kenneth R

A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo. [electronic resource] - Angiogenesis 2009 - 287-96 p. digital

Publication Type: Journal Article

1573-7209

10.1007/s10456-009-9151-7 doi


Administration, Oral
Angiogenesis Inhibitors--administration & dosage
Animals
Cell Movement--drug effects
Cells, Cultured
Endothelial Cells--drug effects
Female
HCT116 Cells
Humans
Mice
Mice, Inbred C57BL
Mice, Nude
Mice, Transgenic
Models, Biological
Neoplasms--drug therapy
Oximes--administration & dosage
Phenylurea Compounds--administration & dosage
Protein Kinase Inhibitors--administration & dosage
Substrate Specificity
Vascular Endothelial Growth Factor A--pharmacology
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors
Xenograft Model Antitumor Assays