LaMontagne, Kenneth R
A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo. [electronic resource]
- Angiogenesis 2009
- 287-96 p. digital
Publication Type: Journal Article
ISSN: 1573-7209
Standard No.: 10.1007/s10456-009-9151-7 doi
Subjects--Topical Terms: Administration, Oral Angiogenesis Inhibitors--administration & dosage Animals Cell Movement--drug effects Cells, Cultured Endothelial Cells--drug effects Female HCT116 Cells Humans Mice Mice, Inbred C57BL Mice, Nude Mice, Transgenic Models, Biological Neoplasms--drug therapy Oximes--administration & dosage Phenylurea Compounds--administration & dosage Protein Kinase Inhibitors--administration & dosage Substrate Specificity Vascular Endothelial Growth Factor A--pharmacology Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors Xenograft Model Antitumor Assays