TY  - GEN
AU  - Yu,Huang-Ping
AU  - Hsieh,Pei-Wen
AU  - Chang,Yi-Ju
AU  - Chung,Pei-Jen
AU  - Kuo,Liang-Mou
AU  - Hwang,Tsong-Long
TI  - DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats
SN  - 1873-2968
PY  - 2009///1019
KW  - Adult
KW  - Animals
KW  - Benzamides
KW  - chemistry
KW  - Benzoates
KW  - Bronchoalveolar Lavage Fluid
KW  - Cyclic AMP
KW  - biosynthesis
KW  - Cyclic AMP-Dependent Protein Kinases
KW  - analysis
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Leukocyte Elastase
KW  - antagonists & inhibitors
KW  - Lung Injury
KW  - etiology
KW  - Lymphocyte Activation
KW  - drug effects
KW  - Male
KW  - Molecular Structure
KW  - N-Formylmethionine Leucyl-Phenylalanine
KW  - pharmacology
KW  - Neutrophils
KW  - Phosphodiesterase Inhibitors
KW  - Proteins
KW  - Random Allocation
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Respiratory Burst
KW  - Shock, Hemorrhagic
KW  - metabolism
KW  - Superoxides
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bcp.2009.06.008
ER  -