Yu, Huang-Ping <br/><br/>
DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats.  [electronic resource] 

 -  Biochemical pharmacology  Oct 2009 
 - 983-92 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-2968 
<br/><br/><label>Standard No.: </label>10.1016/j.bcp.2009.06.008  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Animals<br/>Benzamides--chemistry<br/>Benzoates--chemistry<br/>Bronchoalveolar Lavage Fluid--chemistry<br/>Cyclic AMP--biosynthesis<br/>Cyclic AMP-Dependent Protein Kinases--analysis<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Inhibitory Concentration 50<br/>Leukocyte Elastase--antagonists & inhibitors<br/>Lung Injury--etiology<br/>Lymphocyte Activation--drug effects<br/>Male<br/>Molecular Structure<br/>N-Formylmethionine Leucyl-Phenylalanine--pharmacology<br/>Neutrophils--drug effects<br/>Phosphodiesterase Inhibitors--chemistry<br/>Proteins--analysis<br/>Random Allocation<br/>Rats<br/>Rats, Sprague-Dawley<br/>Respiratory Burst<br/>Shock, Hemorrhagic--metabolism<br/>Superoxides--antagonists & inhibitors