Alvarez, X Anton Reduced TNF-α and increased IGF-I levels in the serum of Alzheimer's disease patients treated with the neurotrophic agent cerebrolysin. [electronic resource] - The international journal of neuropsychopharmacology Aug 2009 - 867-72 p. digital Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't ISSN: 1469-5111 Standard No.: 10.1017/S1461145709990101 doi Subjects--Topical Terms: AgedAged, 80 and overAlzheimer Disease--bloodAmino Acids--therapeutic useBiomarkers--bloodCognition--drug effectsDisability EvaluationDose-Response Relationship, DrugDouble-Blind MethodDown-RegulationEnzyme-Linked Immunosorbent AssayFemaleHumansInsulin-Like Growth Factor I--metabolismMaleMiddle AgedNeuropsychological TestsNootropic Agents--therapeutic usePlacebo EffectSeverity of Illness IndexSpainTime FactorsTreatment OutcomeTumor Necrosis Factor-alpha--bloodUp-Regulation