Canobbio, Ilaria

Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets. [electronic resource] - Blood Sep 2009 - 2193-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2009-03-208074 doi


15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid--pharmacology
Amino Acid Motifs--genetics
Animals
Blood Platelets--enzymology
Enzyme Activation--drug effects
Fibrinogen--metabolism
Isoenzymes--genetics
Mice
Mice, Knockout
Phosphatidylinositol 3-Kinases--genetics
Phosphorylation--drug effects
Platelet Adhesiveness--drug effects
Platelet Aggregation--drug effects
Platelet Glycoprotein GPIIb-IIIa Complex--genetics
Platelet Membrane Glycoproteins--genetics
Proto-Oncogene Proteins c-akt--genetics
Purinergic P2 Receptor Agonists
Receptors, Purinergic P2--genetics
Signal Transduction--drug effects
Vasoconstrictor Agents--pharmacology
rap GTP-Binding Proteins--genetics