TY - GEN AU - Patel,Naina AU - Krishnan,Shekhar AU - Offman,Marc N AU - Krol,Marcin AU - Moss,Catherine X AU - Leighton,Carly AU - van Delft,Frederik W AU - Holland,Mark AU - Liu,Jizhong AU - Alexander,Seema AU - Dempsey,Clare AU - Ariffin,Hany AU - Essink,Monika AU - Eden,Tim O B AU - Watts,Colin AU - Bates,Paul A AU - Saha,Vaskar TI - A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase SN - 1558-8238 PY - 2009///0730 KW - Antineoplastic Agents KW - metabolism KW - Asparaginase KW - Cathepsin B KW - physiology KW - Cell Line KW - Cysteine Endopeptidases KW - Humans KW - Lymphocytes KW - enzymology KW - Lysosomes KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - drug therapy N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI37977 ER -