TY - GEN AU - Grimwade,David AU - Jovanovic,Jelena V AU - Hills,Robert K AU - Nugent,Elizabeth A AU - Patel,Yashma AU - Flora,Rajinder AU - Diverio,Daniela AU - Jones,Katy AU - Aslett,Hannah AU - Batson,Elaine AU - Rennie,Kristian AU - Angell,Roger AU - Clark,Richard E AU - Solomon,Ellen AU - Lo-Coco,Francesco AU - Wheatley,Keith AU - Burnett,Alan K TI - Prospective minimal residual disease monitoring to predict relapse of acute promyelocytic leukemia and to direct pre-emptive arsenic trioxide therapy SN - 1527-7755 PY - 2009///0820 KW - Adult KW - Aged KW - Arsenic Trioxide KW - Arsenicals KW - administration & dosage KW - Blood Chemical Analysis KW - Bone Marrow KW - pathology KW - Cohort Studies KW - Confidence Intervals KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Leukemia, Promyelocytic, Acute KW - drug therapy KW - Male KW - Middle Aged KW - Monitoring, Physiologic KW - methods KW - Multivariate Analysis KW - Neoplasm Recurrence, Local KW - diagnosis KW - Neoplasm, Residual KW - Oncogene Proteins, Fusion KW - genetics KW - Oxides KW - Predictive Value of Tests KW - Probability KW - Prognosis KW - Proportional Hazards Models KW - Prospective Studies KW - Reverse Transcriptase Polymerase Chain Reaction KW - Severity of Illness Index KW - Survival Analysis KW - Treatment Outcome KW - Tretinoin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1200/JCO.2008.20.1533 ER -