Volk, Erin L

The MDM2-a splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf- and p53-null models of tumorigenesis. [electronic resource] - Molecular cancer research : MCR Jun 2009 - 863-9 p. digital

Publication Type: Journal Article

1557-3125

10.1158/1541-7786.MCR-08-0418 doi


Animals
Cell Proliferation--drug effects
Cell Survival--drug effects
Cell Transformation, Neoplastic--chemically induced
Cyclin-Dependent Kinase Inhibitor p16--deficiency
Disease Models, Animal
Ethylnitrosourea
Female
Fibroblasts--metabolism
Male
Mammary Neoplasms, Experimental--chemically induced
Mice
Mice, Inbred C57BL
Mice, Transgenic
Neoplasms, Germ Cell and Embryonal--chemically induced
Protein Isoforms
Proto-Oncogene Proteins c-mdm2--biosynthesis
Tumor Suppressor Protein p53--deficiency