Ménard, Delphine <br/><br/>
Novel potent BRAF inhibitors: toward 1 nM compounds through optimization of the central phenyl ring.  [electronic resource] 

 -  Journal of medicinal chemistry  Jul 2009 
 - 3881-91 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm900242c  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Site<br/>Antineoplastic Agents--chemistry<br/>Inhibitory Concentration 50<br/>Melanoma--drug therapy<br/>Mutation, Missense<br/>Phenols--chemistry<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Pyridines--chemistry<br/>Structure-Activity Relationship