TY  - GEN
AU  - Olive,Kenneth P
AU  - Jacobetz,Michael A
AU  - Davidson,Christian J
AU  - Gopinathan,Aarthi
AU  - McIntyre,Dominick
AU  - Honess,Davina
AU  - Madhu,Basetti
AU  - Goldgraben,Mae A
AU  - Caldwell,Meredith E
AU  - Allard,David
AU  - Frese,Kristopher K
AU  - Denicola,Gina
AU  - Feig,Christine
AU  - Combs,Chelsea
AU  - Winter,Stephen P
AU  - Ireland-Zecchini,Heather
AU  - Reichelt,Stefanie
AU  - Howat,William J
AU  - Chang,Alex
AU  - Dhara,Mousumi
AU  - Wang,Lifu
AU  - Rückert,Felix
AU  - Grützmann,Robert
AU  - Pilarsky,Christian
AU  - Izeradjene,Kamel
AU  - Hingorani,Sunil R
AU  - Huang,Pearl
AU  - Davies,Susan E
AU  - Plunkett,William
AU  - Egorin,Merrill
AU  - Hruban,Ralph H
AU  - Whitebread,Nigel
AU  - McGovern,Karen
AU  - Adams,Julian
AU  - Iacobuzio-Donahue,Christine
AU  - Griffiths,John
AU  - Tuveson,David A
TI  - Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
SN  - 1095-9203
PY  - 2009///0623
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Apoptosis
KW  - drug effects
KW  - Carcinoma, Pancreatic Ductal
KW  - blood supply
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Deoxycytidine
KW  - Disease Models, Animal
KW  - Drug Resistance, Neoplasm
KW  - Hedgehog Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Kruppel-Like Transcription Factors
KW  - metabolism
KW  - Mice
KW  - Neoplasm Transplantation
KW  - Neovascularization, Pathologic
KW  - Pancreatic Neoplasms
KW  - Receptors, G-Protein-Coupled
KW  - Signal Transduction
KW  - Smoothened Receptor
KW  - Stromal Cells
KW  - Veratrum Alkaloids
KW  - Zinc Finger Protein GLI1
KW  - Gemcitabine
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/science.1171362
ER  -