Olive, Kenneth P

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. [electronic resource] - Science (New York, N.Y.) Jun 2009 - 1457-61 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.1171362 doi


Animals
Antineoplastic Agents--administration & dosage
Antineoplastic Combined Chemotherapy Protocols
Apoptosis--drug effects
Carcinoma, Pancreatic Ductal--blood supply
Cell Line, Tumor
Cell Proliferation--drug effects
Deoxycytidine--administration & dosage
Disease Models, Animal
Drug Resistance, Neoplasm
Hedgehog Proteins--antagonists & inhibitors
Humans
Kruppel-Like Transcription Factors--metabolism
Mice
Neoplasm Transplantation
Neovascularization, Pathologic
Pancreatic Neoplasms--blood supply
Receptors, G-Protein-Coupled--antagonists & inhibitors
Signal Transduction--drug effects
Smoothened Receptor
Stromal Cells--drug effects
Veratrum Alkaloids--administration & dosage
Zinc Finger Protein GLI1
Gemcitabine