TY  - GEN
AU  - Shor,Boris
AU  - Cavender,Druie
AU  - Harris,Crafford
TI  - A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice
SN  - 1471-2172
PY  - 2009///1130
KW  - Animals
KW  - B-Lymphocytes
KW  - drug effects
KW  - Carrier Proteins
KW  - genetics
KW  - Catalytic Domain
KW  - Cell Proliferation
KW  - Cells, Cultured
KW  - Embryonic Development
KW  - Gene Knock-In Techniques
KW  - Heterozygote
KW  - Immune System
KW  - embryology
KW  - Lymphocyte Activation
KW  - Mice
KW  - Mutation
KW  - Phosphatidylinositol 3-Kinases
KW  - immunology
KW  - Phosphotransferases (Alcohol Group Acceptor)
KW  - Signal Transduction
KW  - Sirolimus
KW  - pharmacology
KW  - T-Lymphocytes
KW  - TOR Serine-Threonine Kinases
KW  - Tacrolimus Binding Protein 1A
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1186/1471-2172-10-28
ER  -