TY - GEN AU - Fujiwara,Hironori AU - Tabuchi,Masahiro AU - Yamaguchi,Takuji AU - Iwasaki,Koh AU - Furukawa,Katsutoshi AU - Sekiguchi,Kyoji AU - Ikarashi,Yasushi AU - Kudo,Yukitsuka AU - Higuchi,Makoto AU - Saido,Takaomi C AU - Maeda,Sumihiro AU - Takashima,Akihiko AU - Hara,Masahiko AU - Yaegashi,Nobuo AU - Kase,Yoshio AU - Arai,Hiroyuki TI - A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo SN - 1471-4159 PY - 2009///0717 KW - Alzheimer Disease KW - drug therapy KW - Amyloid beta-Peptides KW - metabolism KW - Amyloid beta-Protein Precursor KW - genetics KW - Animals KW - Avoidance Learning KW - drug effects KW - Behavior, Animal KW - Cell Line, Transformed KW - Cell Survival KW - Chromatography, High Pressure Liquid KW - methods KW - Disease Models, Animal KW - Enzyme-Linked Immunosorbent Assay KW - Hydrolyzable Tannins KW - pharmacology KW - Memory KW - Mice KW - Mice, Transgenic KW - Models, Molecular KW - Paeonia KW - chemistry KW - Peptide Fragments KW - Phytotherapy KW - Plant Extracts KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1471-4159.2009.06069.x ER -