Fujiwara, Hironori

A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo. [electronic resource] - Journal of neurochemistry Jun 2009 - 1648-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1471-4159

10.1111/j.1471-4159.2009.06069.x doi


Alzheimer Disease--drug therapy
Amyloid beta-Peptides--metabolism
Amyloid beta-Protein Precursor--genetics
Animals
Avoidance Learning--drug effects
Behavior, Animal--drug effects
Cell Line, Transformed
Cell Survival--drug effects
Chromatography, High Pressure Liquid--methods
Disease Models, Animal
Enzyme-Linked Immunosorbent Assay
Hydrolyzable Tannins--pharmacology
Memory--drug effects
Mice
Mice, Transgenic
Models, Molecular
Paeonia--chemistry
Peptide Fragments--metabolism
Phytotherapy--methods
Plant Extracts--pharmacology
Time Factors