TY - GEN AU - Tsai,Cheng-Yu AU - Ray,Adrian S AU - Tumas,Daniel B AU - Keating,Michael J AU - Reiser,Hans AU - Plunkett,William TI - Targeting DNA repair in chronic lymphocytic leukemia cells with a novel acyclic nucleotide analogue, GS-9219 SN - 1078-0432 PY - 2009///0707 KW - Alanine KW - analogs & derivatives KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - genetics KW - Cell Survival KW - Chromatography, High Pressure Liquid KW - DNA Damage KW - DNA Repair KW - DNA, Neoplasm KW - chemistry KW - Dose-Response Relationship, Drug KW - Guanine KW - Humans KW - Immunoblotting KW - Leukemia, Lymphocytic, Chronic, B-Cell KW - Models, Biological KW - Molecular Structure KW - Organophosphorus Compounds KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Purines KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Tumor Cells, Cultured KW - Ultraviolet Rays KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-08-2848 ER -