TY  - GEN
AU  - Serpillon,Sabrina
AU  - Floyd,Beverly C
AU  - Gupte,Rakhee S
AU  - George,Shimran
AU  - Kozicky,Mark
AU  - Neito,Venessa
AU  - Recchia,Fabio
AU  - Stanley,William
AU  - Wolin,Michael S
AU  - Gupte,Sachin A
TI  - Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH
SN  - 1522-1539
PY  - 2009///0812
KW  - Animals
KW  - Blood Glucose
KW  - metabolism
KW  - Diabetes Mellitus, Type 2
KW  - genetics
KW  - Endothelium, Vascular
KW  - physiopathology
KW  - Fatty Acids, Nonesterified
KW  - blood
KW  - Gene Expression Regulation, Enzymologic
KW  - Glucosephosphate Dehydrogenase
KW  - biosynthesis
KW  - Glutathione
KW  - Heart Diseases
KW  - etiology
KW  - Hydrogen Peroxide
KW  - Hyperglycemia
KW  - Insulin
KW  - Isometric Contraction
KW  - physiology
KW  - Mitochondria, Heart
KW  - enzymology
KW  - Myocardium
KW  - NADP
KW  - NADPH Oxidases
KW  - Obesity
KW  - Rats
KW  - Rats, Zucker
KW  - Superoxides
KW  - Triglycerides
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1152/ajpheart.01142.2008
ER  -