Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. [electronic resource]
- Toxicological sciences : an official journal of the Society of Toxicology Jul 2009
- 235-43 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1096-0929
10.1093/toxsci/kfp096 doi
Acetaminophen--toxicity Analgesics, Non-Narcotic--toxicity Animals Biomarkers--analysis Cell Death--genetics Cell Proliferation--drug effects Chemical and Drug Induced Liver Injury--genetics Gene Expression--drug effects Humans Liver--pathology Male Mice Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide--drug effects Population Principal Component Analysis RNA--biosynthesis Species Specificity Toxicogenetics--standards Transcription, Genetic--drug effects