TY  - GEN
AU  - Beckham,Simone A
AU  - Piedrafita,David
AU  - Phillips,Carolyn I
AU  - Samarawickrema,Nirma
AU  - Law,Ruby H P
AU  - Smooker,Peter M
AU  - Quinsey,Noelene S
AU  - Irving,James A
AU  - Greenwood,Deanne
AU  - Verhelst,Steven H L
AU  - Bogyo,Matthew
AU  - Turk,Boris
AU  - Coetzer,Theresa H
AU  - Wijeyewickrema,Lakshmi C
AU  - Spithill,Terry W
AU  - Pike,Robert N
TI  - A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites
SN  - 1878-5875
PY  - 2009///0610
KW  - Animals
KW  - Catalytic Domain
KW  - Cathepsin B
KW  - antagonists & inhibitors
KW  - Cathepsins
KW  - Cystatins
KW  - metabolism
KW  - Cysteine Proteinase Inhibitors
KW  - pharmacology
KW  - Enzyme Activation
KW  - drug effects
KW  - Fasciola hepatica
KW  - Gastrointestinal Tract
KW  - enzymology
KW  - Humans
KW  - Kinetics
KW  - Life Cycle Stages
KW  - Molecular Probes
KW  - chemistry
KW  - Parasites
KW  - Protein Transport
KW  - Sheep
KW  - Structural Homology, Protein
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.biocel.2009.02.003
ER  -