TY  - GEN
AU  - Zhou,Jinming
AU  - Geng,Guoyan
AU  - Wu,Jian Hui
TI  - Synthesis and in vitro characterization of ionone-based chalcones as novel antiandrogens effective against multiple clinically relevant androgen receptor mutants
SN  - 1573-0646
PY  - 2010///0709
KW  - Androgen Antagonists
KW  - chemical synthesis
KW  - Androgen Receptor Antagonists
KW  - Antineoplastic Agents, Hormonal
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Chalcones
KW  - Drug Design
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - Drug Screening Assays, Antitumor
KW  - Humans
KW  - Male
KW  - Molecular Structure
KW  - Mutation
KW  - Norisoprenoids
KW  - Receptors, Androgen
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10637-009-9251-7
ER  -