TY  - GEN
AU  - Yuan,Haodan
AU  - Li,Na
AU  - Lai,Yurong
TI  - Evaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs
SN  - 1521-009X
PY  - 2009///0928
KW  - Alkaline Phosphatase
KW  - metabolism
KW  - Animals
KW  - Caco-2 Cells
KW  - enzymology
KW  - Drug Delivery Systems
KW  - Drug Stability
KW  - Fluconazole
KW  - administration & dosage
KW  - Half-Life
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Intestinal Absorption
KW  - Intestines
KW  - cytology
KW  - Male
KW  - Mucous Membrane
KW  - drug effects
KW  - Organophosphates
KW  - Phenytoin
KW  - analogs & derivatives
KW  - Phosphates
KW  - Prodrugs
KW  - pharmacology
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Solubility
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.108.026245
ER  -