TY  - GEN
AU  - Lee,Tina X
AU  - Packer,Mark D
AU  - Huang,Jie
AU  - Akhmametyeva,Elena M
AU  - Kulp,Samuel K
AU  - Chen,Ching-Shih
AU  - Giovannini,Marco
AU  - Jacob,Abraham
AU  - Welling,D Bradley
AU  - Chang,Long-Sheng
TI  - Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells
SN  - 1879-0852
PY  - 2009///0707
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Humans
KW  - Mice
KW  - Mice, SCID
KW  - Mice, Transgenic
KW  - Neurilemmoma
KW  - metabolism
KW  - Neuroma, Acoustic
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - Pyrazoles
KW  - Pyruvate Dehydrogenase Acetyl-Transferring Kinase
KW  - Schwann Cells
KW  - cytology
KW  - Signal Transduction
KW  - Sulfonamides
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.ejca.2009.03.013
ER  -