Lee, Tina X <br/><br/>
Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.  [electronic resource] 

 -  European journal of cancer (Oxford, England : 1990)  Jun 2009 
 - 1709-20 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1879-0852 
<br/><br/><label>Standard No.: </label>10.1016/j.ejca.2009.03.013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Proliferation--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Evaluation, Preclinical--methods<br/>Humans<br/>Mice<br/>Mice, SCID<br/>Mice, Transgenic<br/>Neurilemmoma--metabolism<br/>Neuroma, Acoustic--metabolism<br/>Phosphorylation--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Pyrazoles--pharmacology<br/>Pyruvate Dehydrogenase Acetyl-Transferring Kinase<br/>Schwann Cells--cytology<br/>Signal Transduction--drug effects<br/>Sulfonamides--pharmacology<br/>Tumor Cells, Cultured<br/>Xenograft Model Antitumor Assays