Fu, Jingyan

A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2009 - 6939-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.0900833106 doi


Amino Acid Sequence
Amino Acids--genetics
Aurora Kinase A
Aurora Kinase B
Aurora Kinases
Chromosomal Proteins, Non-Histone--metabolism
Chromosome Structures--metabolism
Conserved Sequence
Enzyme Activation
Glycine--genetics
HeLa Cells
Humans
Microtubule-Associated Proteins--metabolism
Mitosis
Models, Molecular
Phosphorylation
Protein Binding
Protein Serine-Threonine Kinases--chemistry
Protein Structure, Quaternary
Protein Structure, Tertiary
Sequence Alignment
Substrate Specificity