Duffield-Lillico, Anna J

Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway. [electronic resource] - Cancer prevention research (Philadelphia, Pa.) Apr 2009 - 322-9 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1940-6215

10.1158/1940-6207.CAPR-09-0005 doi


Arachidonate 5-Lipoxygenase--drug effects
Arachidonic Acid--metabolism
Celecoxib
Cyclooxygenase 2--metabolism
Cyclooxygenase 2 Inhibitors--pharmacology
Female
Humans
Leukotriene E4--urine
Male
Middle Aged
Pneumonia--chemically induced
Prostaglandins E--metabolism
Pyrazoles--pharmacology
Signal Transduction
Smoking--adverse effects
Sulfonamides--pharmacology