TY - GEN AU - Fu,Wei AU - Ma,Qiuping AU - Chen,Lei AU - Li,Pengfei AU - Zhang,Mu AU - Ramamoorthy,Sivapriya AU - Nawaz,Zafar AU - Shimojima,Tsukasa AU - Wang,Hengbin AU - Yang,Yonghua AU - Shen,Zheng AU - Zhang,Yingtao AU - Zhang,Xiaohong AU - Nicosia,Santo V AU - Zhang,Yanping AU - Pledger,Jack W AU - Chen,Jiandong AU - Bai,Wenlong TI - MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation SN - 0021-9258 PY - 2009///0707 KW - Animals KW - Apoptosis KW - Cell Line KW - Cell Nucleus KW - metabolism KW - Cytoprotection KW - Forkhead Transcription Factors KW - Gene Expression Regulation KW - Humans KW - Mice KW - Phosphorylation KW - Protein Binding KW - Protein Processing, Post-Translational KW - Protein Transport KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-mdm2 KW - chemistry KW - Tumor Suppressor Protein p53 KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M901758200 ER -