TY  - GEN
AU  - Nudelman,Igor
AU  - Rebibo-Sabbah,Annie
AU  - Cherniavsky,Marina
AU  - Belakhov,Valery
AU  - Hainrichson,Mariana
AU  - Chen,Fuquan
AU  - Schacht,Jochen
AU  - Pilch,Daniel S
AU  - Ben-Yosef,Tamar
AU  - Baasov,Timor
TI  - Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations
SN  - 1520-4804
PY  - 2009///0602
KW  - Aminoglycosides
KW  - chemical synthesis
KW  - Animals
KW  - Bacteria
KW  - drug effects
KW  - COS Cells
KW  - Cadherin Related Proteins
KW  - Cadherins
KW  - genetics
KW  - Cell Survival
KW  - Chlorocebus aethiops
KW  - Codon, Nonsense
KW  - Cystic Fibrosis Transmembrane Conductance Regulator
KW  - Cytoplasm
KW  - Disease
KW  - Drug Discovery
KW  - Dystrophin
KW  - Gentamicins
KW  - pharmacology
KW  - Hearing Loss
KW  - chemically induced
KW  - Humans
KW  - Oligoribonucleotides
KW  - chemistry
KW  - Paromomycin
KW  - Protein Biosynthesis
KW  - RNA Stability
KW  - RNA, Ribosomal
KW  - Temperature
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1021/jm801640k
ER  -