Nudelman, Igor <br/><br/>
Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations.  [electronic resource] 

 -  Journal of medicinal chemistry  May 2009 
 - 2836-45 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm801640k  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoglycosides--chemical synthesis<br/>Animals<br/>Bacteria--drug effects<br/>COS Cells<br/>Cadherin Related Proteins<br/>Cadherins--genetics<br/>Cell Survival--drug effects<br/>Chlorocebus aethiops<br/>Codon, Nonsense--drug effects<br/>Cystic Fibrosis Transmembrane Conductance Regulator--genetics<br/>Cytoplasm--drug effects<br/>Disease--genetics<br/>Drug Discovery<br/>Dystrophin--genetics<br/>Gentamicins--pharmacology<br/>Hearing Loss--chemically induced<br/>Humans<br/>Oligoribonucleotides--chemistry<br/>Paromomycin--pharmacology<br/>Protein Biosynthesis--drug effects<br/>RNA Stability--drug effects<br/>RNA, Ribosomal--chemistry<br/>Temperature