TY - GEN AU - Offner,Halina AU - Firestein,Gary S AU - Boyle,David L AU - Pieters,Raymond AU - Frincke,James M AU - Garsd,Armando AU - White,Steven K AU - Reading,Christopher L AU - Auci,Dominick L TI - An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis SN - 1521-0103 PY - 2009///0623 KW - Animals KW - Anti-Inflammatory Agents KW - administration & dosage KW - Antibodies KW - immunology KW - Antibody Formation KW - drug effects KW - Arthritis, Rheumatoid KW - chemically induced KW - Collagen KW - Cytokines KW - genetics KW - Dehydroepiandrosterone KW - Disease Models, Animal KW - Gene Expression KW - Hypersensitivity, Delayed KW - Immune System KW - Interleukin-6 KW - Joints KW - Lipopolysaccharides KW - pharmacology KW - Lymph Nodes KW - Male KW - Matrix Metalloproteinase 3 KW - Mice KW - Mice, Inbred DBA KW - Mice, Inbred ICR KW - NF-kappa B KW - metabolism KW - Spleen N1 - Publication Type: Journal Article UR - https://doi.org/10.1124/jpet.108.145086 ER -