TY  - GEN
AU  - Lester,Henry A
AU  - Xiao,Cheng
AU  - Srinivasan,Rahul
AU  - Son,Cagdas D
AU  - Miwa,Julie
AU  - Pantoja,Rigo
AU  - Banghart,Matthew R
AU  - Dougherty,Dennis A
AU  - Goate,Alison M
AU  - Wang,Jen C
TI  - Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery
SN  - 1550-7416
PY  - 2009///0723
KW  - Acetylcholine
KW  - metabolism
KW  - Animals
KW  - Drug Discovery
KW  - Endoplasmic Reticulum
KW  - drug effects
KW  - Epilepsy, Frontal Lobe
KW  - genetics
KW  - Hippocampus
KW  - Mice
KW  - Models, Biological
KW  - Muscle Proteins
KW  - biosynthesis
KW  - Mutation, Missense
KW  - Nerve Tissue Proteins
KW  - Neurotransmitter Agents
KW  - physiology
KW  - Nicotine
KW  - pharmacokinetics
KW  - Parkinson Disease
KW  - prevention & control
KW  - Receptors, Nicotinic
KW  - Smoking
KW  - Tobacco Use Disorder
KW  - Up-Regulation
KW  - Ventral Tegmental Area
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
UR  - https://doi.org/10.1208/s12248-009-9090-7
ER  -