Lester, Henry A <br/><br/>
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.  [electronic resource] 

 -  The AAPS journal  Mar 2009 
 - 167-77 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review 
<br/><br/><label>ISSN: </label>1550-7416 
<br/><br/><label>Standard No.: </label>10.1208/s12248-009-9090-7  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholine--metabolism<br/>Animals<br/>Drug Discovery<br/>Endoplasmic Reticulum--drug effects<br/>Epilepsy, Frontal Lobe--genetics<br/>Hippocampus--drug effects<br/>Mice<br/>Models, Biological<br/>Muscle Proteins--biosynthesis<br/>Mutation, Missense<br/>Nerve Tissue Proteins--biosynthesis<br/>Neurotransmitter Agents--physiology<br/>Nicotine--pharmacokinetics<br/>Parkinson Disease--prevention & control<br/>Receptors, Nicotinic--biosynthesis<br/>Smoking--metabolism<br/>Tobacco Use Disorder--genetics<br/>Up-Regulation--drug effects<br/>Ventral Tegmental Area--drug effects