Montie, Heather L

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. [electronic resource] - Human molecular genetics Jun 2009 - 1937-50 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddp115 doi


Androgens--metabolism
Animals
Autophagy
Cell Line
Cell Nucleus--genetics
Cells, Cultured
Cytoplasm--genetics
Disease Models, Animal
Humans
Male
Mice
Mice, Transgenic
Motor Activity
Motor Neurons--cytology
Muscular Atrophy, Spinal--genetics
Nuclear Localization Signals--genetics
Peptides--genetics
Protein Transport
Receptors, Androgen--genetics
Trinucleotide Repeat Expansion